Possible causes

– Faulty Cruise Control Multifunction Switch
– Cruise Control Multifunction Switch harness is open or shorted
– Cruise Control Multifunction Switch circuit poor electrical connection

Symptoms

– Engine Light ON (or Service Engine Soon Warning Light)
– Cruise control system inoperative

P0581 Information for specific makes

P0581 FORD
P0581 CHRYSLER
P0581 DODGE
P0581 JEEP
P0581 MAZDA
P0581 MITSUBISHI